SRC enhanced cisplatin resistance in bladder cancer by reprogramming glycolysis and pentose phosphate pathway
Abstract The development of cisplatin resistance Smoker often results in a grim prognosis in advanced or recurrent bladder cancer.However, effective treatment strategies for cisplatin resistance have not been well established.Herein, we found that overactivation of SRC is associated with cisplatin-resistance.SRC activates hexokinase2 which up-regul